Evaluation of a nurse-led program for the prevention of complications of long-term glucocorticoids (COCORTICO): study protocol for a randomized trial.

ABSTRACT:

Background

Long-term glucocorticoids are widely prescribed for autoimmune and inflammatory diseases, but their use is associated with a wide range of adverse events, some of which can be severe. Patient education on toxicity and preventive strategies is essential, yet many patients do not receive sufficient information. In some areas, nurse-led therapeutic programs have been developed to optimize care. However, no standardized, institutionally supported education program exists to prevent the adverse events of long-term glucocorticoid therapy.

Methods

We are conducting a superiority, open-label, parallel-group, randomized trial, comparing a nurse-led interdisciplinary program with standard of care, across five French hospitals. Eligible participants are adult patients initia

SUBMITTER: Nicol S 

PROVIDER: S-EPMC12625073 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature