Cardiorespiratory Response to Exercise in Parkinson's Disease: Associations with Autonomic Dysfunction and Physical Activity.

ABSTRACT:

Background

Both autonomic dysfunction and low levels of physical activity could contribute to reduced cardiorespiratory fitness in people with Parkinson's disease (PD). However, the interrelationship between these concepts is not well understood.

Objectives

Our aim was to gain more insight into autonomic dysfunction and physical activity in relation to cardiorespiratory fitness in PD.

Methods

We included 59 individuals with PD (37% women, mean age 65.1 years; mean disease duration 4.5 years; Hoehn and Yahr stage 1-3). All participants completed a cardiopulmonary exercise test (CPET). We examined the association between parameters assessed during a CPET (peak oxygen consumption [VO_2peak], maximum heart rate [HR_max], heart rate recovery at 1 and 3 

SUBMITTER: Veldkamp KI 

PROVIDER: S-EPMC12625118 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature