Air pollution exposure and multimorbidity patterns: evidence from a national cohort study in China.

ABSTRACT:

Background

Multimorbidity prevalence in China has been rising annually and has emerged as a major health challenge. While air pollution contributes to individual Noncommunicable diseases (NCDs), its impact on distinct multimorbidity patterns remains unclear.

Methods

This prospective cohort study analyzed 36,144 participants from the China Family Panel Studies (2010-2022) without baseline multimorbidity. Among 6,839 individuals (18.9%) who developed multimorbidity during median 8-year follow-up, latent class analysis identified distinct disease patterns. Fine-Gray subdistribution hazard models assessed associations between eleven air pollutants (PM2.5, PM10, O3, NO2, SO2, CO, and five PM2.5 components) and pattern-specific multimorbidity.

Results

Four multimorbidity pa

SUBMITTER: Cao Y 

PROVIDER: S-EPMC12625229 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature