Serum miR-141-3p serves as a biomarker for early-stage diagnosis of endometriosis.

ABSTRACT:

Objective

This study is conducted to investigate whether serum microRNA (miR)-141-3p can serve as a biomarker for early-stage diagnosis of endometriosis.

Methods

A total of 246 patients who underwent laparoscopic examination and were diagnosed with endometriosis at our hospital between October 2020 and October 2022 were retrospectively enrolled as the Endometriosis group. This group was further allocated into Early-Endometriosis (Stage I-II) and Severe-Endometriosis (Stage III-IV) groups. Additionally, 87 healthy women with normal clinical parameters during the same period were selected as the control group. miR-141-3p expression in the serum of endometriosis patients were detected using RT-qPCR. The relationship of serum miR-141-3p expression with EHP-30 score in endometrio

SUBMITTER: Tan H 

PROVIDER: S-EPMC12625237 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature