Associations between six cumulative insulin resistance-related indices and incident stroke in individuals with different glucose regulation statuses: a national cohort study in China.

ABSTRACT:

Background

Stroke continues to be a predominant contributor to morbidity and mortality, with insulin resistance (IR) recognized as a significant risk factor. The predictive utility of cumulative IR-related indices for assessing stroke risk across varying glucose regulation statuses remains ambiguous. The present study investigated the associations between six cumulative IR-related indices-triglyceride-glucose (TyG) index, triglyceride-glucose-body mass index (TyG-BMI), Chinese visceral adiposity index (CVAI), metabolic score for insulin resistance (METS-IR), atherogenic index of plasma (AIP), and estimated glucose disposal rate (eGDR)-and stroke risk in individuals with abnormal glucose regulation (AGR) compared to those with normal glucose regulation (NGR).

Methods

Data fro

SUBMITTER: Huang W 

PROVIDER: S-EPMC12625373 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature