Incidence trend analysis of human brucellosis in the context of human development: an ecological study using joinpoint regression in Iran.

ABSTRACT:

Background

Human brucellosis (HB) remains a significant public health concern in Iran, where its burden may be shaped by socio-developmental factors. This ecological time trend analysis explores long-term patterns in HB incidence in the context of human development.

Methods

We conducted Joinpoint regression analysis to assess temporal trends in HB incidence from 2000 to 2023 in Iran. The Human Development Index (HDI) was included as a predictor to examine associations using Spearman correlation and linear regression on log-transformed HDI. Residual diagnostics and robust regression techniques were applied.

Results

The overall annual percentage change (AAPC) in HB incidence showed a slight but statistically significant upward trend (+ 0.45%; p = 0.023). Joinpoint regre

SUBMITTER: Hamyali-Ainvand M 

PROVIDER: S-EPMC12625387 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature