Comparison of bispectral index and patient state index during general anesthesia with remimazolam.

ABSTRACT:

Background

Processed electroencephalographic indices, such as the Bispectral Index (BIS) and Patient State Index (PSI), are widely used to assess anesthetic depth; however, their comparative behavior under remimazolam remains unclear. In practice, either index may deviate from its target range despite stable anesthesia, and the response of the companion monitor is uncertain. This study examined whether the two indices moved in parallel or diverged when one departed from its nominal range during remimazolam anesthesia.

Methods

In this prospective, single-center study, BIS and PSI were simultaneously recorded at 21 predefined time points from induction to emergence in 60 adults who received remimazolam-based general anesthesia. Remimazolam was induced at 12 mg/kg/h and maintai

SUBMITTER: Shiraishi T 

PROVIDER: S-EPMC12625464 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature