Diffusion-T2 correlated spectroscopy imaging to explore possible placental composition changes over gestation.

ABSTRACT:

Background

Placenta plays a vital role for fetal growth and development during pregnancy. Currently, antenatal noninvasive imaging techniques to directly evaluate placental function remains challenge. Diffusion-T2 correlated spectroscopy imaging (DT2SI) can provide compositional information for different organs in-vivo. The aim of this study was to investigate the use of DT2SI as a tool to elucidate the placental composition change over gestation in healthy pregnancy.

Methods

Forty healthy singleton pregnancies were retrieved from our placental MRI research database. MRI was performed at 23.1-36.0 weeks of gestational age (GA) in a 3.0T system. DT2SI measurements were performed using DWI sequence with 7 b-values combining 4 TEs. ROIs were manually defined inside placenta on

SUBMITTER: Liu X 

PROVIDER: S-EPMC12625514 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature