Comparison of remimazolam and dexmedetomidine for conscious sedation in elderly patients undergoing dental implant surgery: a prospective randomized controlled trial.

ABSTRACT:

Background

The objective of this study was to compare the efficacy and safety of remimazolam and dexmedetomidine in elderly patients undergoing dental implant surgery.

Methods

Seventy-four elderly patients aged 65-80 years and scheduled for dental implant surgery were randomly divided into two groups. Patients in Group R received a 0.05 mg/kg loading dose of remimazolam over 1 min and followed by an infusion rate 0.1-0.3 mg/kg/h. In Group D, a 0.5 µg/kg bolus of dexmedetomidine was given over 10 min and followed by an infusion rate 0.2-1.0 µg/kg/h. The primary outcome of the study was the incidence of hypotension between the two groups. Secondary outcomes were perioperative complications, hemodynamic and respiratory variables, sedation and recovery profiles.

Results

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SUBMITTER: Gao P 

PROVIDER: S-EPMC12625583 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature