Time to Full Enteral Feeds and Late-Onset Sepsis in Extremely Preterm Infants.

ABSTRACT:

Importance

Recent studies suggest that early achievement of full enteral feeding improves clinical outcomes among preterm infants.

Objective

To examine the association between full enteral feeding and late-onset sepsis.

Design, setting, and participants

This secondary analysis of a cohort study prospectively followed up a multicenter cohort of preterm infants with gestational ages ranging from 23 to 28 weeks born between January 1, 2012, and December 31, 2021, at 19 US academic centers. Infants without major anomalies who received enteral feedings and survived beyond postnatal day 7 were included.

Exposure

Full enteral feeding (≥120 mL/kg/d).

Main outcomes and measures

The primary outcome was the incidence of late-onset sepsis confirmed through culture-p

SUBMITTER: Salas AA 

PROVIDER: S-EPMC12625685 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature