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Hypothyroidism in spontaneous coronary artery dissection: presentation, clinical and angiographic findings, management and outcomes.


ABSTRACT:

Background

Hypothyroidism has been suggested as a predisposing and prognostic factor in patients with spontaneous coronary artery dissection (SCAD), but evidence in this regard is very limited.

Methods

This study sought to compare differences in clinical presentation, angiographic findings, management and outcomes between SCAD patients with (H-SCAD) and without (NH-SCAD) a history of hypothyroidism from the prospective nation-wide Spanish SCAD Registry.

Results

Overall, 47 H-SCAD (12%) and 342 NH-SCAD patients were included. H-SCAD patients when compared with NH-SCAD patients were significantly older (57±10 vs 54±12 years, p=0.045), had more frequent dyslipidaemia (49% vs 31%, p=0.013) and a non-significant trend to more associated fibromuscular dysplasia (47% vs 30%,

SUBMITTER: Camacho Freire SJ 

PROVIDER: S-EPMC12625887 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature