Predicting adolescent disordered eating and behaviours: exploring environmental moderators of polygenic risk.

ABSTRACT:

Background

Both genetic and environmental factors contribute to the risk of developing disordered eating, with twin studies demonstrating environmental factors moderate genetic susceptibility. To date, gene-environment interactions leveraging polygenic risk scores (PRS) have not been studied in disordered eating phenotypes beyond anorexia nervosa (AN). This study investigated if polygenic risk for AN interacts with established environmental eating disorder risk factors (parental expectations, parental criticism, parental conflict, parental care and weight-related peer teasing) to predict overall levels of disordered eating in the general population or specific lifetime disordered eating behaviours (avoidance of eating, objective bulimic episodes, self-induced vomiting and driven ex

SUBMITTER: Curtis M 

PROVIDER: S-EPMC12626179 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature