Lesion mimic gene <i>HLM1</i> positively regulates cell death and disease resistance in rice.

ABSTRACT: Lesion mimic mutants are important resources for deciphering the molecular mechanism of programmed cell death (PCD) and defense response in plants. Here, we isolated a new dominant lesion mimic mutant, Hlm1, which exhibited a hypersensitive response (HR) like phenotype with excessive accumulation of reactive oxygen species (ROS) and constitutive expression of pathogenesis-related (PR) genes, displayed a spontaneous cell death and enhanced resistance to rice bacterial blight pathogens as well. Genetic analysis indicates that the lesion mimic phenotype of Hlm1 is controlled by a dominant allele, which is tightly linked to a T-DNA insertion in rice chromosome 2, and a candidate gene OsNRAT1, encoding the Nramp (natural resistance-associated macrophage protein) alum

SUBMITTER: Zhang P 

PROVIDER: S-EPMC12627016 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature