Dynamic evolution of postoperative hemodynamics in moyamoya angiopathy: a quantitative assessment of 4D Flow MRI and prognostic relevance.

ABSTRACT:

Purpose

The hemodynamic mechanisms underlying revascularization efficacy in moyamoya angiopathy (MMA) and their prognostic implications remain incompletely characterized. This study leverages four-dimensional flow magnetic resonance imaging (4D Flow MRI) to investigate longitudinal hemodynamic changes at the carotid siphons of MMA patients undergoing revascularization, and to evaluate their association with surgical outcomes.

Methods

A prospective cohort of 35 consecutive MMA patients undergoing unilateral revascularization was enrolled at West China Hospital from July 2018 to January 2020. Using 4D Flow MRI, hemodynamic parameters, including mean/maximum flow, velocity, and wall shear stress, were quantified in the ipsilateral and contralateral carotid siphons at three time

SUBMITTER: Xia C 

PROVIDER: S-EPMC12627057 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature