A global soil plasmidome resource unveils functional and ecological roles of plasmids in soil microbiomes.

ABSTRACT: Plasmids play significant roles in microbial adaptation to ecosystems, yet their dynamics remain poorly understood due to identification challenges. We present the Global Soil Plasmidome Resource (GSPR), a comprehensive dataset of 98,728 plasmid sequences amassed from 6860 terrestrial microbial communities and isolates. We explore this resource through various computational approaches, including phylogenetic diversity analysis, host prediction, and extensive functional annotation, to understand the contribution of plasmids to the genetic and functional diversity in soil, correlating these findings with sample type, as well as the soil habitat they were retrieved from. Our analysis reveals insights into plasmid-encoded functions such as effector modules, quorum sensing, and stress resistanc

SUBMITTER: Fiamenghi MB 

PROVIDER: S-EPMC12627491 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature