Association between frailty and cognitive function: a pooled analysis of three ageing cohorts.

ABSTRACT: Cross-sectional evidence suggested that frailty was an important risk factor for cognitive impairment. However, previous studies only focused on baseline frailty status, not taking into consideration the dynamic changes in frailty status during follow-up. This study aimed to investigate the associations between changes in frailty status and cognitive impairment. This study used data from three prospective cohorts: China Health and Retirement Longitudinal Study (CHARLS), Health and Retirement Study (HRS) and English Longitudinal Study of Ageing (ELSA). Frailty status was evaluated by the frailty index and classified as robust, pre-frailty, or frailty. Cognitive function was assessed by memory, orientation and executive function. Linear mixed regression model was used to evaluate the longitu

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12627544 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature