Conservation and variability of long-range interactions in structurally diverse maize genomes.

ABSTRACT: Chromatin interactions play critical roles in gene regulation. The genomes of distinct maize inbreds exhibit substantial structural variation, however, F₁ hybrids lead to significant hybrid vigor. The long-range genomic interactions present in different inbreds and their hybrid offspring have not been assessed in maize. Here, we perform H3K4me3/H3K27ac HiChIP in two maize inbreds and their reciprocal F₁ hybrids. We identify interactions specific to inbred or hybrid genotypes. Some genes involved in hybrid-specific interactions show dominant or over-dominant expression patterns. The analysis of the inbred-specific or shared interactions between two parental inbred lines in the hybrids reveal unexpected gain or loss of interactions compared to the parents. The unexpecte

SUBMITTER: Liu H 

PROVIDER: S-EPMC12627579 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature