Stereotactic body radiotherapy versus laparoscopic liver resection for single hepatocellular carcinoma ≤ 5 cm: a retrospective, multicenter, cohort study.

ABSTRACT: To compare the efficacy of stereotactic body radiotherapy (SBRT) and laparoscopic liver resection (LLR) for patients with single hepatocellular carcinoma (HCC) ≤ 5 cm. A retrospective analysis was conducted on a cohort of patients with HCC who underwent either LLR or SBRT at our centers. Recurrence-free survival (RFS) and overall survival (OS) were estimated using the Kaplan-Meier method and compared between groups using the log-rank test. To reduce selection bias, propensity score matching (PSM) was applied. Subgroup analyses were also performed to explore outcomes across different clinical and tumor-related characteristics. This retrospective cohort study included 383 patients from four hospitals between January 2017 and December 2019, with 268 patients in the LLR group and 115 in the SB

SUBMITTER: Zhou B 

PROVIDER: S-EPMC12627700 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature