Clinical outcomes of liposomal and conventional bupivacaine in postoperative pain management in female patients following thoracoscopic lung surgery.

ABSTRACT: This study compared liposomal bupivacaine (LB) and conventional bupivacaine hydrochloride (BH) for postoperative pain management among 50 female patients undergoing uniportal thoracoscopic lung surgery. The patients were randomized to LB (n = 25) or BH (n = 25) groups based on the intercostal nerve blocks they received post-surgery. Outcomes included intraoperative vital signs, pain scores (static/dynamic visual analog scale [VAS]), and adverse reactions (nausea, vomiting, and dizziness) assessed at 6, 24, 48, and 72 h. Intraoperative vital signs (heart rate [HR], blood pressure, oxygen saturation, and bispectral index) and anesthetic/vasoactive drug administration exhibited no significant differences between groups. Postoperatively, the LB group demonstrated superior short-term analgesia,

SUBMITTER: Lu D 

PROVIDER: S-EPMC12627712 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature