Evidence for a severe cognitive subgroup in a comprehensive neuropsychological Post-COVID-19 syndrome classification.

ABSTRACT: Approximately 7% of adults develop Post-COVID-19 syndrome (PCS). Cognitive impairment is common, but its profile in PCS is not well defined and requires clearer differentiation from general (post-)illness effects. The aim of this study was to identify distinct cognitive profiles in PCS and to characterize them with respect to broader psychological factors such as fatigue, depression, anxiety, and personality. To this end, we assessed cognition, fatigue, depression, anxiety, and personality traits in PCS patients, convalescents (CV), healthy controls (HC), and post-viral syndrome patients (PV) of different etiology. Cognitive performance was assessed with an extensive protocol covering multiple cognitive domains, including verbal and nonverbal short-term memory, verbal and nonverbal working

SUBMITTER: Balz LT 

PROVIDER: S-EPMC12627843 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature