Association between alcoholic beverage consumption and cerebral small vessel disease burden.

ABSTRACT:

Background

The relationship between alcohol consumption and cerebral small vessel disease (CSVD) remains uncertain, particularly regarding drinking patterns and beverage types. We investigated how total alcohol intake, drinking frequency, and beverage-specific consumption are associated with CSVD burden using cross-sectional data.

Methods

We included 27,326 UK Biobank (UKB) participants with MRI data, among whom 21,130 were current drinkers with full alcohol intake data. Alcohol consumption (frequency and beverage type) was self-reported. CSVD burden was measured via normalized white matter hyperintensity volume (WMHV) on T2-FLAIR MRI. Multivariable linear regression models adjusted for demographics, lifestyle, and vascular risk factors were used to examine associations.

SUBMITTER: Xiong BB 

PROVIDER: S-EPMC12627891 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature