Multimodal Pharmacological Assessment of <i>Arenga porphyrocarpa</i> Palm Leaves and Stems Extracts: Insights From In Vivo, In Vitro, and In Silico Approaches.

ABSTRACT: Arenga porphyrocarpa palm tree roots and buds are used to treat urinary incontinence, fever, appetite loss, and as a diuretic. Our study aimed to evaluate the neuropharmacological, antioxidant, cytotoxic, and thrombolytic potentials of A. porphyrocarpa leaf and stem extracts through in vivo, in vitro and in silico studies. Different fractions of A. porphyrocarpa leaves and stems were investigated for anxiolytic and anti-depressant efficacy through EPM and HBT and TST and FST tests. The anti-oxidant assessment was assessed by using DPPH and reducing power assays, while thrombolytic efficacy was analyzed by clot lysis technique. Computational methods like in silico molecular docking, pass prediction and ADME/T were applied to evaluate several pharmacological properties o

SUBMITTER: Azad JH 

PROVIDER: S-EPMC12628079 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature