Identifying clustering in patterns of late effects among survivors of adolescent and young adult Hodgkin lymphoma.

ABSTRACT:

Background

We examined late effects clustering among adolescent and young adult (AYA; age 15-39 years at diagnosis) Hodgkin lymphoma (HL) survivors and identified characteristics associated with each cluster.

Methods

We included AYAs with HL in 2006-2018 from the California and Utah Cancer Registries linked to statewide hospitalization, emergency department, and ambulatory surgery visit data. We identified severe late effects >2 years after cancer diagnosis in 9 late effects categories. Latent class analysis (LCA) was used to identify late effects clusters. Multinomial logistic regression models estimated adjusted associations of demographic and treatment characteristics with LCA late effect group.

Results

We identified 4635 AYA HL survivors with median follow-up of 8

SUBMITTER: Parker K 

PROVIDER: S-EPMC12628312 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature