Diagnostic Efficacy and Clinical Impact of Image-guided Core Needle Biopsy of Suspected Adult Nonvertebral Osteomyelitis.

ABSTRACT:

Objectives

The diagnostic yield and clinical impact of image-guided core needle biopsy (ICNB) of suspected nonvertebral osteomyelitis in adults is heterogenous in published studies because of small sample size, indicating the need for large cohort studies.

Methods

A retrospective analysis of ICNBs was performed from 2010 to 2021 for patients with suspected nonvertebral osteomyelitis. For each biopsy, a series of factors were analyzed, as well as if histopathology was diagnostic of osteomyelitis and if microbiological cultures were positive. Additionally, it was recorded in what way biopsy influenced clinical management regarding antimicrobial treatment. Multivariate statistical analysis was performed to evaluate the factors associated with yield.

Results

A total of 88

SUBMITTER: Winkler WL 

PROVIDER: S-EPMC12628504 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature