A J-shaped association between weight-adjusted waist index and cardiovascular disease: a longitudinal study from the CHARLS database.

ABSTRACT:

Background

Weight-adjusted waist index (WWI) is a new obesity-related index, which has advantages in assessing central obesity. The aim of this study was to investigate the relationship between WWI and cardiovascular disease (CVD).

Methods

We collected a nationally representative sample of middle-aged and older adults over 45 years of age from the China Health and Retirement Longitudinal Study (CHARLS). WWI was calculated by dividing waist circumference by the square root of body weight, whereas CVD was defined as self-reported having heart disease and/or stroke. We used restricted cubic spline (RCS) curves to investigate whether there is a nonlinear relationship between WWI and CVD. Subsequently, a two-piece linear regression model was developed, and a recursive algorithm w

SUBMITTER: Wang J 

PROVIDER: S-EPMC12628520 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature