Risk factors for new vertebral compression fracture following percutaneous vertebral augmentation: a systematic review and meta-analysis based on multivariate logistic regression analysis.

ABSTRACT:

Objective

This meta-analysis investigates the prevalence and risk factors for new vertebral compression fractures (NVCF) following percutaneous vertebral augmentation (PVA) in patients with osteoporotic vertebral compression fractures (OVCF).

Methods

We searched PubMed, Cochrane Library, Embase, and Web of Science (up to June 2025) and screened case-control and cohort studies that utilized multivariate logistic regression analysis to examine the prevalence and risk factors of NVCF after PVA in OVCF patients. The meta-analysis was performed according to the PRISMA guidelines. After data extraction, STATA 15.0 was used to calculate the pooled odds ratio (OR) and 95% confidence interval (CI).

Results

This meta-analysis included 18 studies involving 7,743 patients, of who

SUBMITTER: Liu S 

PROVIDER: S-EPMC12628626 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature