High-throughput and genome-guided optimization of exopolysaccharide production in marine bacteria for sustainable biotechnology.

ABSTRACT: Marine bacteria are an untapped resource for exopolysaccharides (EPS) with broad potential applications in biomedicine, bioremediation, and food industries. However, industrial utilization remains limited due to low yields and strain-specific variability. This study explores seven novel marine bacterial strains (Limnobacter alexandrii LZ-4, Nioella ostreopsis Z7-4, Mesorhizobium alexandrii Z1-4, Marinobacter shengliensis subsp. Alexandrii LZ-6, Marinobacter alexandrii LZ-8, Memelialla alexandrii LZ-28, and Sulfitobacter alexandrii AM1-D1) isolated from marine dinoflagellate microbiota. A genome-guided, high-throughput fermentation strategy was employed to optimize EPS production. Genomic analysis identified distinct EPS biosynthesis pathways

SUBMITTER: Wei Y 

PROVIDER: S-EPMC12628687 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature