Chemical signaling in reaction networks generates corresponding mechanical impulses.

ABSTRACT: Chemical reaction networks (CRNs) in the body are directed pathways that transmit reagents to reactive sites and trigger chemical processes, which ultimately instigate the appropriate physical activity. Typically, models for CRNs do not describe the coupling among chemistry, hydrodynamics and fluid-structure interactions that inherently arise in fluids. Herein, we develop a model that describes the above interrelated physicochemical behavior and show that chemical transport in a CRN spontaneously gives rise to transduction of chemistry into mechanical work, to form a complementary chemo-mechanical network (CMN). To simulate CRNs, we use the repressilator model, a reaction pathway involving biomimetic feedback loops. The encompassing material system is formed from an ordered array of enzyme

SUBMITTER: Shklyaev OE 

PROVIDER: S-EPMC12628728 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature