Ontology highlight
ABSTRACT: Introduction
Automated insulin delivery (AID) systems continuously deliver insulin subcutaneously, reducing the burden of managing type 1 diabetes mellitus (T1D). However, there are limited data comparing different insulin delivery modalities, particularly regarding their impact on health-related quality of life (HRQoL). This study aimed to quantify the disutility associated with conventional insulin delivery modalities and utility gains associated with wearable, on-body, AID systems.Methods
Health state vignettes representing different insulin delivery modalities were developed based on interviews with people with T1D alongside published literature and validated by experts. Utility values were elicited via the time trade-off (TTO) method from the general population in the
SUBMITTER: Elliott J
PROVIDER: S-EPMC12628749 | biostudies-literature | 2025 Dec
REPOSITORIES: biostudies-literature