Differential hypo-osmotic stress responses and regulatory mechanisms of <i>Aspergillus sydowii</i> in amphipod guts and hadal sediments.

ABSTRACT: Hadal amphipods, which play a vital role in deep-sea ecosystems, harbor gut microbiota that significantly influence host physiology and environmental adaptation. However, understanding of the culturable gut fungi remains limited, particularly their response to the deep-sea osmotic environment. Here, this study reports the successful isolation of Aspergillus sydowii XTO612 from the gut of Hysterocrates gigas. Comparative physiological profiling with A. sydowii DM1, originating from hadal sediment, revealed significant interspecific divergence in hypo-osmotic stress responses (0.1 M NaCl). Low osmolarity conditions were applied as an environmental stressor, and alterations in secondary metabolites, metabolic activity, micromorphology, and reactive oxygen species were obs

SUBMITTER: Wang Z 

PROVIDER: S-EPMC12628754 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature