A computational reference for human genomics analysis in (poly)phenol research.

ABSTRACT: (Poly)phenols are bioactive compounds found in plant-based food. They have been associated with numerous health-promoting features. To date, several research studies are investigating their contribution to human health and disease by applying different omics techniques. However, a standard reference for human genomics investigation is missing, limiting the current understanding and knowledge on the impact of (poly)phenols on humans when using omics approaches. In this study, we present a computational functional investigation of 121 candidate human genes involved in (poly)phenol absorption, distribution, metabolism, and excretion to propose a standard reference for genomics analyses in personalised nutrition and health research. Starting from genomics information, this reference framework

SUBMITTER: Treccani M 

PROVIDER: S-EPMC12628759 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature