Using wastewater surveillance to investigate community-level differences in antibacterial resistance in a major urban center, USA.

ABSTRACT: Wastewater surveillance could be a low-cost strategy for assessing patterns of antibiotic resistance across urban populations. We quantified fluoroquinolone-resistant (FQ-R) Enterobacterales, third-generation cephalosporin-resistant (3GC-R) Enterobacterales, carbapenem-resistant Enterobacterales, and the bla_CTX-M-group 1 and bla_KPC genes in influent wastewater from 12 diverse sewersheds across metro Atlanta over two seasons; examined associations between culture- and digital PCR-based outcomes; and investigated relationships between sewersheds' sociodemographic characteristics and concentrations of antibiotic-resistant bacteria in wastewater. FQ-R Enterobacterales, 3GC-R Escherichia coli, and 3GC-R Klebsiella, Enterobacter, or Cit

SUBMITTER: Goetgeluck C 

PROVIDER: S-EPMC12628767 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature