Cumulative triglyceride-glucose index and hypertension risk: a longitudinal cohort study.

ABSTRACT:

Background

Prior research has established a positive association between the single-measured triglyceride-glucose (TyG) index and hypertension. Nevertheless, longitudinal studies addressing the enduring impact of TyG index on incident hypertension are lacking. This study sought to explore the association between cumulative TyG index (cum-TyG) and incident hypertension, especially obesity-related hypertension (ORHT).

Methods

A total of 21,017 individuals [mean (SD) age: 48.5 ± 11.7 years, male (%): 14,544 (69.2)] without hypertension were recruited from the Kailuan Study. The cum-TyG was determined by multiplying the mean TyG index by the time intervals between successive visits. Multivariable Cox regression models were used to investigate the association of cum-TyG with inci

SUBMITTER: Wu Z 

PROVIDER: S-EPMC12628851 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature