Association of serum uric acid to high-density lipoprotein cholesterol ratio with all-cause mortality and cardiovascular disease mortality in patients with gout.

ABSTRACT:

Background

The uric acid to high-density lipoprotein cholesterol ratio (UHR), a novel biomarker, has clinical value in diagnosing and evaluating metabolic syndrome, diabetes mellitus, and atherosclerosis. However, the relationship between UHR and mortality in gout patients is unknown.This study aimed to investigate UHR's link to all-cause and cardiovascular mortality in gout patients.

Methods

Based on NHANES data from 2007 to 2018, 1,479 gout patients who completed follow-up as of December 31, 2018 were included, and patients were divided into four groups using UHR, we analyzed the relationship between UHR and risk of death using Cox regression models, tested for nonlinear relationships with a restricted cubic spline, and assessed for population heterogeneity by stratifying

SUBMITTER: Lou X 

PROVIDER: S-EPMC12628874 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature