Biomarkers influence kidney function estimates more so than race among persons with HIV.

ABSTRACT:

Background

We sought to understand the results of using different estimating equations (with and without a "race" category) and the addition of cystatin C as a biomarker on Chronic Kidney Disease (CKD) stage estimates among persons with HIV (PWH), for whom CKD is an important comorbidity.

Methods

Biomarkers were measured in this cross-sectional single site U.S. clinic-based study from 2014 to 2016. Other laboratory and clinical data were abstracted from the electronic health record based on the last recorded value proximal to the study visit. Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) glomerular filtration estimating equations with and without cystatin C were applied to categorize CKD stage, and staging agreement was assessed using the difference of proporti

SUBMITTER: Obeng-Nyarkoh PA 

PROVIDER: S-EPMC12629064 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature