Global, regional, and national burdens of late-onset epilepsy in adults aged 65 years and older from 1990 to 2021: A population-based study.

ABSTRACT:

Objective

Epilepsy remains one of the most widespread and severe neurological disorders worldwide. This study aims to evaluate the burden of late-onset epilepsy (LOE) and investigate its temporal trends and inequalities among older adults at global, regional, and national scales between 1990 and 2021.

Methods

This analysis utilizes data from the 2021 Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Temporal trends in the age-standardized prevalence rate (ASPR), incidence rate (ASIR), mortality rate (ASMR), and disability-adjusted life years (DALYs) rate for LOE were quantified through the calculation of average annual percentage change over the study period.

Results

In 2021, the global ASPR and ASIR of LOE in adults aged 65 and older were estimated a

SUBMITTER: Wang Z 

PROVIDER: S-EPMC12629476 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature