Candidacidal effect of Moringa stabilized silver nanomaterials reveal disruption of cell wall integrity, efflux pump, vacuole homeostasis and virulence traits in Candida auris.

ABSTRACT: Candida auris (C. auris) is known as a superbug characterized by its high prevalence of multi-drug resistance, causing outbreaks in healthcare settings and leading to high mortality rates worldwide. Developing novel and efficient measures to combat its spread and mitigate its impact on patient outcomes is pertinent. This study describes a simple and eco-friendly method for synthesizing silver nanocomposites and silver-zinc nanocomposites using leaf extract of the Moringa Oleifera (MO), plant. The synthesized nanocomposite was characterized and confirmed by several techniques like Fourier Transform Infrared Spectroscopy (FTIR), X-ray diffractometry (XRD), Thermogravimetric Analysis (TGA), X-ray Photoelectron Spectroscopy (XPS), Scanning electron microscopy (SEM). Moreover, nanocomposites we

SUBMITTER: Nahvi I 

PROVIDER: S-EPMC12629489 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature