High-concentration (8%) capsaicin patch for chronic postoperative neuropathic pain: A systematic review of randomised controlled trials.

ABSTRACT:

Background

Chronic postoperative neuropathic pain is a common and sometimes disabling problem. Mainstay pharmacological management involves gabapentinoids, tricyclic anti-depressants and serotonin and norepinephrine reuptake inhibitors. Past this, guidance is limited. There is good evidence for the use of high-concentration capsaicin patch in non-operative causes of neuropathic pain. This systematic review aimed to evaluate the evidence base for the high-concentration (8%) capsaicin patch for postoperative neuropathic pain.

Methods

We carried out a systematic search of 4 databases (Ovid MEDLINE, Embase, Cochrane Library and https://ClinicalTrials.gov) from inception to 3rd July 2025 to identify randomised controlled trials investigating the effectiveness of high-concentratio

SUBMITTER: Niven M 

PROVIDER: S-EPMC12629964 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature