Effects of Akkermansia muciniphila on growth, antioxidant status and jejunal transcriptome in LPS-stressed yellow-feathered broilers.

ABSTRACT: The aim of this study was to investigate the effect of Akkermansia muciniphila (AKK) on growth performance, serum antioxidant parameters and jejunal transcriptome in lipopolysaccharide (LPS)-stressed yellow-feathered broilers. A total of 80 male yellow-feathered broilers were randomly divided into four treatment groups: control group (Control); intraperitoneal injection of 0.5 mg LPS /kg BW (LPS); oral gavage of 1 mL (10⁸ CFU/mL) AKK (AKK); and oral gavage of 1 mL (10⁸ CFU/mL) AKK plus intraperitoneal injection 0.5 mg LPS /kg BW (AKKLPS). The study lasted for 21 days. The results showed that final body weight, average daily gain and feed intake were significantly lower in the LPS group than the other three groups (P<0.05). The weight and index of bursa of Fabricius of

SUBMITTER: Zhu R 

PROVIDER: S-EPMC12630029 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature