Clinical Evaluation of T Component in the Ninth Edition TNM Classification of Thymic Epithelial Tumors.

ABSTRACT:

Objectives

The optimal staging system for thymic epithelial tumors (TETs) remains controversial. This study aimed to evaluate the clinical utility of the T component in the latest ninth edition of the TNM staging system.

Methods

A retrospective analysis was performed on patients diagnosed with TETs at our center from January 2001 to December 2022. Recurrence-free survival (RFS) and overall survival (OS) were analyzed using Kaplan-Meier curves and Cox proportional hazards regression models. The predictive performance of the TNM staging systems was mainly assessed by the concordance index (C-index) and area under the receiver operating characteristic curve (AUC).

Results

Ultimately, 545 patients with TETs were included. The ninth edition TNM staging system demonstrated

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12630076 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature