Modulation of response inhibition with event-related atVNS showed EEG but no behavioral effects.

ABSTRACT: Response inhibition can be explained within the theory of event coding. Event file binding and reconfiguration have previously been studied in relation to various neurotransmitters. We aimed to activate the noradrenergic system through auricular transcutaneous vagus nerve stimulation (atVNS) to study effects on response inhibition. Forty healthy participants completed a Go/Nogo task under verum and sham phasic event-related atVNS stimulation with concomitant EEG measurement. The Go/Nogo task was designed to assess response inhibition with feature overlap between Go and Nogo trials requiring reconfiguration of event files. In overlapping Go trials, reaction times increased, and accuracy decreased compared to non-overlapping trials. False alarm rates were higher in overlapping Nogo trials. T

SUBMITTER: Becker LF 

PROVIDER: S-EPMC12630591 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature