Clinical characteristics of Torquetenovirus infected immunocompromised patients explored by metagenomic next-generation sequencing.

ABSTRACT: Since the recent application of metagenomic next-generation sequencing (mNGS) techniques to clinics, Torquetenoviruses (TTV) have received much attention due to their high positive rates. However, there is an insufficient understanding in clinical settings of the pathogen, especially in immunocompromised patients. This study explores the clinical characteristics of TTV infection in immunocompromised patients using mNGS. We enrolled a total of 120 TTV-infected patients in the study, including 81 immunocompromised and 39 immunocompetent individuals. The prevalence, diagnosis, treatment, and co-pathogens were compared between the two groups. The microbial diversity and presence of co-pathogens in patients infected with Torquetenovirus (TTV) were elucidated through comprehensive analysis. T-te

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC12630796 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature