Mechanical stress-mediated immune and inflammatory regulation: <b>a</b> bibliometric and visualization analysis of mechanoimmunology based on two databases.

ABSTRACT:

Background

With advances in detection technologies and the trend of interdisciplinary integration, mechanical stress in biomechanics has been shown to exert broad effects on organisms. It influences multiple cellular processes, including proliferation, migration, and differentiation, and also plays a critical regulatory role in both immune cell function and the organismal immune-inflammatory response. Thus, an emerging interdisciplinary field-mechanoimmunology-has emerged. However, the specific mechanisms underlying this field remain incompletely elucidated. Herein, this study aims to identify the latest research hotspots and provide a thorough analysis of the current research status in this domain.

Methods

A total of 1,901 articles were retrieved from the Web of Science Cor

SUBMITTER: Pang J 

PROVIDER: S-EPMC12631210 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature