Sustainable Extraction of Alkaloids from <i>Worsleya procera</i>: Improving the Method with Green Chemistry.

ABSTRACT: Green chemistry seeks to develop safer, more efficient, and environmentally sustainable processes, particularly for the extraction of bioactive compounds from natural sources. In this study, Worsleya procera, a chemically underexplored species of the Amaryllidaceae family, was investigated as a source of alkaloids with therapeutic potential. To the best of our knowledge, this work represents the first systematic comparison of multiple traditional and green extraction workflows applied to this species. Several protocols were evaluated using conventional solvents (methanol, hexane) and greener alternatives (ethanol, heptane), with or without modifications in the extraction steps. The optimized protocol reduced solvent use by ∼46.5% and simplified the workflow while maintaining extract

SUBMITTER: Duque Rodrigues W 

PROVIDER: S-EPMC12631677 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature