Association Between Sensorineural Hearing Loss and Neurocognitive Performance in Survivors of Childhood Cancer: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Various studies have shown that sensorineural hearing loss (SNHL) is associated with neurocognitive impairment among childhood cancer survivors, though prior studies are limited by small sample sizes and inconsistent methods.

Objective

This systematic review and meta-analysis aimed to quantify neurocognitive differences between survivors with severe SNHL (s-SNHL) and those without.

Methods

Studies were included if they evaluated childhood cancer survivors (diagnosed ≤ 21 years), were ≥ 2 years posttreatment, received cranial radiation and/or platinum-based chemotherapy, used validated neurocognitive tests, and included survivors with and without SNHL. Methods and reporting adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PR

SUBMITTER: Schlak JE 

PROVIDER: S-EPMC12631741 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature