Epidemiology of Plasmodium spp. Detection Among Acute Febrile Illness Patients in Two Regions of Nigeria.

ABSTRACT:

Background

Malaria is a common cause of acute febrile illness (AFI) in Nigeria.

Methods

Patients presenting with AFI at two tertiary hospitals were enrolled from August 2023 to September 2024. Specimens were screened for 25 pathogens using a multi-pathogen screening assay. Demographic, seasonal, clinical, and environmental associations with Plasmodium spp. detection via the assay are described and analyzed. An exploratory analysis of climatic predictors for percent positivity was conducted. Other pathogens detected, alongside Plasmodium spp., are reported.

Results

Plasmodium spp. was detected in 293 (24.4%) enrollees. Larger household size (crude odds ratio [COR] = 3.70, 95% confidence interval [CI] = 1.12-12.28), being a healthcare worker (COR = 3.39, CI = 1.22-9.41)

SUBMITTER: Quiner CA 

PROVIDER: S-EPMC12631765 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature