Associations of Long-Term Exposure to Temperature Variability with Glucose Metabolism: Results from KORA F4 and FF4.

ABSTRACT: The impact of rising temperature variability driven by climate change on metabolic health remains understudied, especially considering the global increase in diabetes prevalence, with long-term effects on glucose metabolism unexplored. This study investigated associations between long-term temperature variability exposure and glucose metabolism in a population-based cohort of 2997 participants (4954 observations) over a 7-year period from KORA F4 and FF4 cohorts in Augsburg, Germany. Long-term exposure to temperature variability was estimated as the standard deviation of the daily mean air temperature over the 365-day period preceding each examination. We applied generalized estimating equations to examine the longitudinal associations between long-term exposure to temperature variability

SUBMITTER: Ni W 

PROVIDER: S-EPMC12631984 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature