Age-specific antibody profiles of respiratory syncytial virus after COVID-19 pandemic: a sero-epidemiological survey in Taizhou City, Eastern China.

ABSTRACT:

Background

The generalizability of the current quantitative assessments of age-specific RSV antibody levels remains unclear in China. We aimed to comprehensively understand the RSV immune profile at the population level and identify related factors.

Methods

We conducted a community-based cross-sectional sero-epidemiological study in Taizhou City, Eastern China, from June 2 to 30, 2024, and assessed RSV pre-F IgG antibody titres. We employed generalized linear models to identify factors linked to antibody titres and used a generalized additive model to determine RSV seropositivity risk. The serocatalytic model was further used to estimate the force of infection (FOI) based on age-specific seroprevalence data.

Results

Among 1303 individuals aged 16 months to 93 years, t

SUBMITTER: Zheng B 

PROVIDER: S-EPMC12632124 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature