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Diagnostic feasibility study of stereoscopic optical palpation for breast tumour margin assessment.


ABSTRACT:

Purpose

Optical elastography has been developed for intraoperative tumour margin assessment during breast-conserving surgery (BCS), based on the elevated stiffness of tumour. It aims to assist the surgeon in removing all cancerous tissue in a single operation, reducing re-excision surgeries and potentially lowering recurrence rate. In this study, we investigate the use of a new, cost‑effective method called stereoscopic optical palpation (SOP), a camera‑based optical elastography technique, for breast cancer detection. We tested its diagnostic feasibility on tissue samples from 48 patients.

Experimental design

SOP was performed on the margins of freshly excised breast tissue from 48 patients. For each specimen, pairs of photographs were taken, and within two minutes, detaile

SUBMITTER: Fang Q 

PROVIDER: S-EPMC12632133 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature