Probing the core metabolism of <i>Cereibacter sphaeroides</i> by transposon mutagenesis.

ABSTRACT: During phototrophic growth, Cereibacter sphaeroides can use several carbon substrates that are central carbon intermediates (e.g., succinate and L-malate) or that require only a few steps to enter central carbon metabolism (e.g., acetate and D-malate). In addition, with light as the energy source, the carbon substrate provided will function as a carbon source for cell carbon synthesis only. Therefore, C. sphaeroides is ideally suited to understand the changes necessary to switch between different carbon sources and, consequently, to redirect carbon flow in central carbon metabolism. This study describes C. sphaeroides transposon mutants that have lost the ability to use one or more of the organic carbon sources 3-hydroxypropionate, acetate, L-malate, propionate/HCO

SUBMITTER: Alber BE 

PROVIDER: S-EPMC12632250 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature